Monday 6 April 2020

How does animal feel when shut down in zoo ?

Human has invaded water,earth ,sky and what not to satisfy their own desire which knows no limits.But how much injustice to other species would mother  nature  tolerate?. I am a human  by birth but with  a simple heart like innocent animals  who knows no  corruption. The creator of all animate and inanimate  has listened your prayer.Every action has a reaction . Hey ,all the innocent souls (animals ,birds and all other species in jungle ,cages,zoo,water and sky)  ,do not cry ,smile .A good news for you all .Come see.Human is beaten mercilessly  by God(in police uniform) when seen outside house to save them from corona demon for which  there is no medicine  available to treat or prevent.I would request all the animals to read the small story below







Friday 3 April 2020

Developing antibody tests for SARS-CoV-2

Developing antibody tests for SARS-CoV-2 


Because, in Bosch's words, the spike protein is the sole viral protein responsible for entry into the host cell, its stability as SARS-CoV-2 mutates is important for understanding whether re-infection with a novel strain is likely. Wang says that the spike protein is highly conserved. Virologists generally agree that media reports of reinfection with SARS-CoV-2 are most likely due to erroneous PCR tests. Hibberd argues that once people produce antibodies against a particular coronavirus, they probably have immunity for life. Indeed, Wang's laboratory has investigated how long immunity against SARS-CoV and Middle East respiratory syndrome coronavirus lasts. “17 years later, a SARS survivor still has neutralising antibodies against SARS—we found that not only were the antibodies there, but they could still neutralise the SARS virus.”

Friday 27 March 2020

The occlutech duct occluder

Transcaval access for transcatheter aortic valve replacement: Use of Brockenbrough needle

ranscaval access is a completely percutaneous route from the inferior cava vein, through the retroperitoneal interstitial space and into the abdominal aorta to allow therapeutic procedures, such as transcatheter aortic valve replacement. It is an alternative to access to the femoral artery when the iliofemoral arteries are too small or too diseased to accommodate the desired introducer sheath. Transcaval access to the aorta is based on the observation that the interstitial hydrostatic pressure exceeds the venous pressure. As a result, in the retroperitoneal space, blood that leaves the abdominal aortic returns to the venous circulation through a hole in the cava vein, instead of being accumulated as hemorrhage. This physiology allows the large transcave sheaths to be temporarily removed during tract repair and allows the aortocaval tracts to be closed with nitinol occluding devices [5]. The traditional transcaval access is described with the use of a rigid-tip coronary CTO guidewire, aided by microcatheter and electrocautery, which is advanced in a calcium-free target in the aorta. Then, the system is exchanged by stiff support guide and delivery system is advanced through a fistula cava-aorta to deploy the valve [6]. In our case, we decided to use the Brockenbrough needle. This allowed us, with the help of pressure measurement in the tip of the needle and the image fusion, not only to know when we entered the abdominal aorta, but also having a better support. It was very important to choose a zone without calcium and avoiding iliac bifurcation and renal arteries to proximal. The next steps were the usual, and finally, the closure of the fistula aortic vein was made and there was not access complications. In the literature, there is no reference to transcaval access with the use of Brockenbrought needle.



Sunday 15 March 2020

During oxidation of succinic acid 2 electrons are transferred from succinic acid to oxygen.the redox potential generated by oxidation reduction system is 0.79 volts.calculate the amount of energy released during oxidation of 1 mole of succinic acid is 

The crawling tumour

Sunday 19 January 2020

coronary artery angiograghic views

Rotation describes the position of the image intensifier around the longitudinal axis of the patient. LAO refers to rotating the camera to the patient's left (catheter and spine will be on the right side of the image), RAO to the patient's right (catheter and spine on the left side of the image). Angulation describes the position of the image intensifier in the short axis of the patient. Camera can pivit toward (cranial) or away (caudal) from the patient's head


Sunday 12 January 2020

The procedure was done under general anesthesia. All the children underwent transesophageal echocardiography (TEE) for reassessment of the defect size and surrounding margins prior to device closure. The ASO was used in all the cases. The device size was selected based on the maximum diameter of the ASD as determined on TEE at 0°, 45°, and 90°. The ASO used was either equal to or about 10% more than the maximum ASD diameter. Balloon sizing was not done in any of the patients. The length of the IAS was measured at 0° and 90° and the longer of the two measurements was used to define the length. Although the IAS length was estimated, it did not determine the maximum size of the device to be used. After obtaining the venous access, heparin was administered in the dose of 100 i.u/kg. Thereafter, 50 i.u./kg of heparin was administered every 30 min if the procedure time extended beyond 60 min. Activated clotting time was not monitored during the procedure. Intravenous (IV) antibiotic was given 1 h before and 8 and 24 h after the procedure. Postprocedure, children were observed for 24 h and were discharged on oral aspirin in the dose of 5 mg/kg/day for 6 months. All of them underwent predischarge ECG and TTE.

Thursday 2 January 2020

DNA copy number variations – Do these big mutations have a big effect on cardiovascular risk?

Short and long-term outcomes of coronary perforation managed by coil embolization: A single-center experience

every interventionalist should know when and how to deploy coils

Successful percutaneous treatment of recurrent post-infarction ventricular septal rupture using an Amplatzer duct occluder







After the VSR was confirmed by left ventriculography ( Fig. 3 A), a Judkins right-4 catheter and 0.035-inch wire was used to cross the defect from the left ventricle to the right ventricle, and the wire was advanced into the pulmonary artery. Then, the wire was snared and exteriorized through the left subclavian vein. The stretch diameter of the defect was measured using a calibrated balloon ( Fig. 3 B), and was found to be 7.8 mm. According to the size of defect and geometric characteristics of the ventricular septal myocardium, ADO 12/10 was selected. A delivery sheath (AMPLATZER TorqVue Delivery System, Abbott, Abbott Park, IL, USA) was advanced from the left subclavian vein through the defect into the left ventricle using an arteriovenous wire loop. Then, the ADO was deployed after ensuring an adequate position using TEE and angiography ( Fig. 3 C), and the device was released successfully. TEE and left ventriculography showed that the device sandwiched the septum and covered the defect well