Cureus | Transcatheter Closure of a Patent Ductus Arteriosus Using a Piccolo Duct Occluder

Cureus | Transcatheter Closure of a Patent Ductus Arteriosus Using a Piccolo Duct Occluder

Cureus | A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large Device

Cureus | A Case of Device Closure of an Eccentric Atrial Septal Defect Using a Large Device

Exercise induced brachial artery pseudoaneurysm treated by balloon assisted direct human thrombin injection: A case report

Exercise induced brachial artery pseudoaneurysm treated by balloon assisted direct human thrombin injection: A case report

Angioplasty to Treat Ostial Left Main and Ostial Right Coronary Artery Critical Stenosis in a Case of Takayasu Arteritis

Angioplasty to Treat Ostial Left Main and Ostial Right Coronary Artery Critical Stenosis in a Case of Takayasu Arteritis

Modified balloon-stent kissing technique avoid side-branch compromise for simple true bifurcation lesions

Modified balloon-stent kissing technique avoid side-branch compromise for simple true bifurcation lesions

Treatment of left main using one stent ,two stents or no stent

Treatment of left main using one stent ,two stents or no stent

Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway and Atrial Flutter: A Case Report

Trio of Rheumatic Mitral Stenosis, Right Posterior Septal Accessory Pathway and Atrial Flutter: A Case Report

Snake Envenomation

 Snake Envenomation

The mammalian IgG molecule (Panel A) consists of an Fc (heavy) chain, a hinge, and two Fab (light) chains. The light chains have constant and variable regions, which allow the IgG to bind to certain antigens (Ag), such as venom components. When the IgG is treated with pepsin, the IgG molecule is cleaved below the hinge (comprising two disulfide bridges), and an F(ab′)2 fragment is produced (Panel B). When the IgG is treated with papain, the cleavage occurs above the hinge, and two Fab fragments are produced (Panel C). The Fc remnant or chain, which is more immunogenic than the Fab chains, can be removed from the remaining solution by means of various purification techniques.